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accelerating rotarod  (Panlab)
86
Panlab accelerating rotarod
WHIM mutants display cerebellar morphological alterations and anxiety-like behavioral phenotypes (A) Voxel-wise comparison of cerebellar brain volumes showing gross morphological abnormalities in P45 WHIM mice. Red: WHIM larger than controls; blue: WHIM smaller than controls; black contours: regions where FWE-corrected ∗ p < 0.05; n > 9 animals/condition. (B) 2D skeleton analysis of white matter arbor vitae. ∗∗ p < 0.01; n > 9 animals/condition. (C) Schematic of mouse dorsal cerebellum. Bar plots and sagittal cerebellar sections at different interaural levels in the vermis and hemisphere. Multiple t test, ∗ p < 0.05, ∗∗ p < 0.01; n > 4 animals/condition. (D) Boxplots showing the time WHIM mice spend in arena and the number of vertical counts. Student’s t test, ∗∗ p < 0.01; n = 16 animals/condition. (E) Line plot indicating the latency to fall (s) from the <t>accelerating</t> <t>rotarod.</t> Two-way ANOVA, ∗ p < 0.05; n = 11 animals/condition. (F) Boxplots showing the number of transitions, the ratio between time in the dark chamber and number of transitions. Student’s t test, ∗ p < 0.05, ∗∗ p < 0.01; n = 16 animals/condition. (G) Boxplot indicating the immobility time (s). Student’s t test, ∗∗ p < 0.01; n = 16 animals/condition. (H) Bar plot indicating the percentage of beads buried. Student’s t test, ∗ p < 0.05; n > 6 animals/condition. (I) Schematics of the experimental plan. (J) Line plot showing body weight from P0 to P45. Multiple t test, ∗ p < 0.05, ∗∗ p < 0.01; n > 17 animals/condition. (K) Line plot showing the time pups gripped the stick. Multiple t test, ∗ p < 0.05; n > 14 animals/condition. (L) Boxplot quantifying the time pups take to turn and face upward. Multiple t test, ∗ p < 0.05; n > 30 animals/condition. (M) Bar plot showing the percentage of pups that turn away from the cliff. Multiple t test, ∗∗ p < 0.01; n > 30 animals/condition.
Accelerating Rotarod, supplied by Panlab, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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accelerating rotarod - by Bioz Stars, 2026-10
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WHIM mutants display cerebellar morphological alterations and anxiety-like behavioral phenotypes (A) Voxel-wise comparison of cerebellar brain volumes showing gross morphological abnormalities in P45 WHIM mice. Red: WHIM larger than controls; blue: WHIM smaller than controls; black contours: regions where FWE-corrected ∗ p < 0.05; n > 9 animals/condition. (B) 2D skeleton analysis of white matter arbor vitae. ∗∗ p < 0.01; n > 9 animals/condition. (C) Schematic of mouse dorsal cerebellum. Bar plots and sagittal cerebellar sections at different interaural levels in the vermis and hemisphere. Multiple t test, ∗ p < 0.05, ∗∗ p < 0.01; n > 4 animals/condition. (D) Boxplots showing the time WHIM mice spend in arena and the number of vertical counts. Student’s t test, ∗∗ p < 0.01; n = 16 animals/condition. (E) Line plot indicating the latency to fall (s) from the accelerating rotarod. Two-way ANOVA, ∗ p < 0.05; n = 11 animals/condition. (F) Boxplots showing the number of transitions, the ratio between time in the dark chamber and number of transitions. Student’s t test, ∗ p < 0.05, ∗∗ p < 0.01; n = 16 animals/condition. (G) Boxplot indicating the immobility time (s). Student’s t test, ∗∗ p < 0.01; n = 16 animals/condition. (H) Bar plot indicating the percentage of beads buried. Student’s t test, ∗ p < 0.05; n > 6 animals/condition. (I) Schematics of the experimental plan. (J) Line plot showing body weight from P0 to P45. Multiple t test, ∗ p < 0.05, ∗∗ p < 0.01; n > 17 animals/condition. (K) Line plot showing the time pups gripped the stick. Multiple t test, ∗ p < 0.05; n > 14 animals/condition. (L) Boxplot quantifying the time pups take to turn and face upward. Multiple t test, ∗ p < 0.05; n > 30 animals/condition. (M) Bar plot showing the percentage of pups that turn away from the cliff. Multiple t test, ∗∗ p < 0.01; n > 30 animals/condition.

Journal: Neuron

Article Title: Neurodevelopmental origins of structural and psychomotor defects in CXCR4-linked primary immunodeficiency

doi: 10.1016/j.neuron.2025.05.016

Figure Lengend Snippet: WHIM mutants display cerebellar morphological alterations and anxiety-like behavioral phenotypes (A) Voxel-wise comparison of cerebellar brain volumes showing gross morphological abnormalities in P45 WHIM mice. Red: WHIM larger than controls; blue: WHIM smaller than controls; black contours: regions where FWE-corrected ∗ p < 0.05; n > 9 animals/condition. (B) 2D skeleton analysis of white matter arbor vitae. ∗∗ p < 0.01; n > 9 animals/condition. (C) Schematic of mouse dorsal cerebellum. Bar plots and sagittal cerebellar sections at different interaural levels in the vermis and hemisphere. Multiple t test, ∗ p < 0.05, ∗∗ p < 0.01; n > 4 animals/condition. (D) Boxplots showing the time WHIM mice spend in arena and the number of vertical counts. Student’s t test, ∗∗ p < 0.01; n = 16 animals/condition. (E) Line plot indicating the latency to fall (s) from the accelerating rotarod. Two-way ANOVA, ∗ p < 0.05; n = 11 animals/condition. (F) Boxplots showing the number of transitions, the ratio between time in the dark chamber and number of transitions. Student’s t test, ∗ p < 0.05, ∗∗ p < 0.01; n = 16 animals/condition. (G) Boxplot indicating the immobility time (s). Student’s t test, ∗∗ p < 0.01; n = 16 animals/condition. (H) Bar plot indicating the percentage of beads buried. Student’s t test, ∗ p < 0.05; n > 6 animals/condition. (I) Schematics of the experimental plan. (J) Line plot showing body weight from P0 to P45. Multiple t test, ∗ p < 0.05, ∗∗ p < 0.01; n > 17 animals/condition. (K) Line plot showing the time pups gripped the stick. Multiple t test, ∗ p < 0.05; n > 14 animals/condition. (L) Boxplot quantifying the time pups take to turn and face upward. Multiple t test, ∗ p < 0.05; n > 30 animals/condition. (M) Bar plot showing the percentage of pups that turn away from the cliff. Multiple t test, ∗∗ p < 0.01; n > 30 animals/condition.

Article Snippet: We used an accelerating rotarod (Panlab, #76-0770).

Techniques: Comparison